23 June 2021

BRIDGE welcomes 14 talented researchers

New Fellows

The BRIDGE – Translational Excellence Programme welcomes its third class of postdoc fellows in translational medicine. Two of the promising new fellows, Emma Louise Louth, working on a treatment for Alzheimer's, and Morten Orebo Holmström, developing better treatment for pancreas cancer, are both highly motivated for stepping out of the lab and obtaining new skills in the translational field.

Hands with gloves

A step towards becoming an independent researcher

PhD Emma Louise Louth, MSc, has always been interested in disease mechanisms in the brain. As part of the BRIGDE fellowship she will explore how the hormone GLP1, known as a frequent treatment for diabetes, can have a positive effect on Alzheimer's disease. Emma will focus on drug delivery across the blood-brain barrier in pre-clinical models of Alzheimer's disease using imaging, and she is optimistic for her participation in BRIDGE:

I'm determined to find out more about basic disease mechanisms in the brain and to understand this novel therapeutic approach to Alzheimer’s disease using GLP1. But my real motivation is when I see that my work has a greater chance for clinical relevance. So, this translational research programme is ideal for someone like me. I will be able to learn from both sides, staying in academia that I know so well and getting closer to the industry through our collaboration with Gubra.

Emma continues:

 I'm really looking forward to take this step towards becoming a more independent researcher and at the same time being able to acquire new skills in imaging techniques, which will enable me to actually see how the GLP1 receptors related to this disease are interacting.

Emma Louise Louth
Emma Louise Louth

Emma Louise Louth's mentors are Professor Martin Lauritzen from the Department of Neuroscience, UCPH,and Principal Scientist Jacob Hecksher-Sørensen from the biotech company Gubra.

New skills in handling big data

PhD Morten Orebo Holmström, MD,  is also joining BRIDGE as a new fellow with a promising translational project. He is working on a method to increase the response level for immune therapy for pancreas cancer. It is well-known that immune therapy has a very low effect in pancreas cancer, partially due to the high amount of two specific cytokines which send signals to weaken the immune system. Cytokines are small proteins that are crucial in regulating the growth and activity of immune system cells and blood cells. Morten and his team will explore how they can enable immune cells to find and kill cells that express the two cytokines. With the expertise of his mentors and courses from the Academic Curriculum tied to the BRIDGE programme, he hopes to get closer to a treatment for pancreas cancer:

My motivation for applying for the BRIDGE programme is to get to the core of translational research. I have great expectations to the very interesting and relevant courses that will improve my ability to handle big data, which I can use in my project and in my career. It will definitely supplement my medical education, which did not focus that much on translational research and the process beyond. So the programme will without a doubt boost my career.

Morten Orebo Holmström
Morten Orebo Holmström

Morten Orebo Holmström’s mentors are Professor Niels Ødum from LEO Foundation Skin Immunology Research Center, UCPH, Clinical Professors Julia Johansen from Department of Oncology and Medicine, Herlev-Gentofte Hospital, and Professor Mads Hald Andersen from Department of Immunology and Microbiology, UCPH, and National Center for Cancer Immune Therapy at Herlev-Gentofte Hospital.  

Upcoming call and important dates

The BRIDGE – Translational Excellence Programme, founded in 2018 with funding from the Novo Nordisk Foundation has expanded its intake from 11 to 14 annual postdoc-fellowships.

The fellows have two to three mentors representing basic biomedical research, the clinical environment and/or the life science industry enabling them to combine methods and insights from the different fields into translational research.  

Stay tuned on www.bridge.ku.dk for the upcoming call fourth call for 14 new translational fellows to enter the BRIDGE – Translational Excellence Programme. Deadline for applicants February 28th, 2022. Project commencement September 1st,  2022. You can also follow the programme on Twitter at UCPH_BRIDGE.